Article  |   December 2004
Outer and Middle Ear Status and Distortion Product Otoacoustic Emissions in Children With Sickle Cell Disease
Author Notes
Hearing Disorders / Special Populations / Genetic & Congenital Disorders
Article   |   December 2004
Outer and Middle Ear Status and Distortion Product Otoacoustic Emissions in Children With Sickle Cell Disease
American Journal of Audiology December 2004, Vol.13, 164-172. doi:10.1044/1059-0889(2004/021)
History: Accepted 28 Apr 2004 , Received 17 Dec 2003 , Revised 19 Mar 2004
American Journal of Audiology December 2004, Vol.13, 164-172. doi:10.1044/1059-0889(2004/021)
History: Accepted 28 Apr 2004 , Received 17 Dec 2003 , Revised 19 Mar 2004

The purpose of this study was to investigate distortion product otoacoustic emissions (DPOAEs) and outer/middle ear status in 12 African American children with normal hearing and homozygous sickle cell disease (SCD) and age-, gender-, and ear-matched African American controls. C. R. Downs, A. Stuart, & D. Holbert (2000) reported that DPOAE amplitudes were significantly larger for children with SCD. Because the integrity of the middle ear system directly influences OAE characteristics, it was felt that concurrent investigation of DPOAE amplitudes and outer/middle ear function in children with SCD was warranted. DPOAEs were evoked by 13 primary-tone pairs with f2 frequencies ranging from 1000 to 4500 Hz. Outer/middle ear status was assessed with tympanometry through indices of peak compensated static acoustic admittance, tympanometric width, tympanometric peak pressure, ear canal volume, and middle ear resonance frequency. Tympanograms were recorded with probe-tone frequencies of 226 and 678 Hz. DPOAE amplitudes were significantly larger for children with SCD (p < .05). There were no group differences in any of the middle ear indices (p > .05). These findings suggest that increased DPOAE amplitudes for children with SCD cannot be attributed to differences in outer/middle ear function as assessed with tympanometry.

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