Effect of Tinnitus on Distortion Product Otoacoustic Emissions Varies With Hearing Loss PurposeThe aim of this study was to measure the effect of tinnitus, while accounting for the effect of hearing loss and aging, on distortion product otoacoustic emissions (DPOAEs).MethodDPOAEs were measured twice in both ears in 5 groups of participants: young adults with normal hearing, middle-age adults with normal hearing, adults ... Research Article
Research Article  |   June 01, 2013
Effect of Tinnitus on Distortion Product Otoacoustic Emissions Varies With Hearing Loss
 
Author Affiliations & Notes
  • Fatima T. Husain
    University of Illinois at Urbana–Champaign
  • Correspondence to Fatima T. Husain: husainf@illinois.edu
  • Editor: Larry Humes
    Editor: Larry Humes×
Article Information
Hearing Disorders / Research Article
Research Article   |   June 01, 2013
Effect of Tinnitus on Distortion Product Otoacoustic Emissions Varies With Hearing Loss
American Journal of Audiology, June 2013, Vol. 22, 125-134. doi:10.1044/1059-0889(2012/12-0059)
History: Received October 29, 2012 , Revised November 23, 2012 , Accepted December 28, 2012
 
American Journal of Audiology, June 2013, Vol. 22, 125-134. doi:10.1044/1059-0889(2012/12-0059)
History: Received October 29, 2012; Revised November 23, 2012; Accepted December 28, 2012

PurposeThe aim of this study was to measure the effect of tinnitus, while accounting for the effect of hearing loss and aging, on distortion product otoacoustic emissions (DPOAEs).

MethodDPOAEs were measured twice in both ears in 5 groups of participants: young adults with normal hearing, middle-age adults with normal hearing, adults with high-frequency sensorineural hearing loss, age-matched adults with similar hearing loss and tinnitus, and adults with normal hearing and chronic tinnitus.

ResultsMultivariate analysis revealed a main effect of hearing loss and age, but no effect of tinnitus, across all 5 groups. Separate tests revealed significant effects of age and tinnitus in the normal-hearing groups and hearing loss in adults with or without tinnitus, but no effect of tinnitus in those with hearing loss.

ConclusionDPOAE levels in the group of adults with hearing loss and tinnitus were diminished, but those in the group with normal hearing and tinnitus were enhanced, relative to DPOAE levels in the controls. Outer hair cell function, as indexed by DPOAEs, exhibits a complex association with tinnitus, and this has implications in the use of DPOAEs as a tool both for testing for tinnitus presence and for creating a model of neural mechanisms underlying tinnitus.

Acknowledgments
I wish to thank Jenise Chappell, Corinne Heller, and Jaclyn Utz for assistance with data collection and Jaclyn Utz and Kwaku Akrofi for assistance with data analysis. The study was supported by funding from the Tinnitus Research Consortium; the Mary J. Neer award from the College of Applied Health Sciences, University of Illinois at Urbana-Champaign; and a Campus Research Board grant, Office of Vice-Chancellor of Research, University of Illinois at Urbana-Champaign.
Order a Subscription
Pay Per View
Entire American Journal of Audiology content & archive
24-hour access
This Article
24-hour access