The Relationship Between Iron Deficiency Anemia and Sensorineural Hearing Loss in the Pediatric and Adolescent Population Purpose A correlation between iron deficiency anemia (IDA) and sudden sensorineural hearing loss (SNHL) was described in adults. In this study, we examined if there is a relationship between IDA and hearing loss in the pediatric population. Method This was a retrospective cohort study of data collected from ... Research Article
Research Article  |   June 13, 2017
The Relationship Between Iron Deficiency Anemia and Sensorineural Hearing Loss in the Pediatric and Adolescent Population
 
Author Affiliations & Notes
  • Kathleen M. Schieffer
    Department of Surgery, Division of Colon and Rectal Surgery, Pennsylvania State University College of Medicine, Hershey
  • James R. Connor
    Department of Neurosurgery, Pennsylvania State University College of Medicine, Hershey
  • James A. Pawelczyk
    Department of Kinesiology, Noll Laboratory, Pennsylvania State University, University Park
  • Deepa L. Sekhar
    Department of Pediatrics, Pennsylvania State University College of Medicine, Hershey
  • Disclosure: The authors have declared that no competing interests existed at the time of publication.
    Disclosure: The authors have declared that no competing interests existed at the time of publication. ×
  • Correspondence to Kathleen M. Schieffer: kschieffer@pennstatehealth.psu.edu
  • Editor: Sumitrajit Dhar
    Editor: Sumitrajit Dhar×
  • Associate Editor: Ryan McCreery
    Associate Editor: Ryan McCreery×
Article Information
Hearing Disorders / Research Articles
Research Article   |   June 13, 2017
The Relationship Between Iron Deficiency Anemia and Sensorineural Hearing Loss in the Pediatric and Adolescent Population
American Journal of Audiology, June 2017, Vol. 26, 155-162. doi:10.1044/2017_AJA-16-0093
History: Received September 26, 2016 , Revised December 28, 2016 , Accepted January 12, 2017
 
American Journal of Audiology, June 2017, Vol. 26, 155-162. doi:10.1044/2017_AJA-16-0093
History: Received September 26, 2016; Revised December 28, 2016; Accepted January 12, 2017

Purpose A correlation between iron deficiency anemia (IDA) and sudden sensorineural hearing loss (SNHL) was described in adults. In this study, we examined if there is a relationship between IDA and hearing loss in the pediatric population.

Method This was a retrospective cohort study of data collected from the Informatics for Integrating Biology and the Bedside database from 2011 to 2016. Children and adolescents 4–21 years old seen at Penn State Milton S. Hershey Medical Center, Hershey, PA, were examined for hearing loss and IDA status. Hearing loss was determined by International Classification of Disease-9 and -10 codes, and IDA was determined by both low hemoglobin and serum ferritin levels for age and sex.

Results We identified 20,113 patients. Prevalence of hearing loss and IDA was 1.7% and 2.3%, respectively. The prevalence of all hearing loss was 3.0% in the IDA cohort and 1.7% in those without IDA. Children and adolescents with IDA are at increased odds of developing SNHL (adjusted odds ratio: 3.67, 95% CI [1.60–7.30]).

Conclusions Children with IDA demonstrate increased likelihood of SNHL. Although correction of IDA in those with hearing loss has yet to be linked to improvements in hearing outcomes, screening for and correcting IDA among pediatric patients will positively affect overall health status.

Supplemental Material: https://doi.org/10.23641/asha.5087071

Acknowledgments
This publication was supported by Institutional Clinical and Translational Science Institute Grant UL1 TR000127 from the National Center for Advancing Translational Sciences. Dr. Sekhar is supported by Grant KL2 TR000126. Kathleen Schieffer is supported by Grant TL1 TR000125.
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